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Hep B vaccine is among the new kids on the block. Although introduced in the industrialzed world in the '80s, its use only took off in the developing countries with GAVI support in the present century. Although some northern European countries were initially reluctant to give the vaccine, based on burden of disease issues, the vaccine is now almost universally given to infants, less universally to health workers and other high risk groups.
On the technical side, this series includes an interesting item from Outer Mongolia, where cold winter temperatures may affect the efficacy of the hep B vaccine, which cannot be frozen. From China and Viet Nam, there is interesting work on hep B, which is highy heat stable, used outside the cold chain.
The chronic carrier state of hep B makes it an unattractive candidate for early eradication, but eradication may become more attractive in future decades, as fresh birth cohorts are protected in greater numbers, and remaining hep B carriers in older age groups play a declining role in transmission of the virus.
A recent Cochrane review shows no RCTs evaluating hep B boosters. For all recently introduced vaccines, the same question arises: how durable is durable protection?
Read it all at www.childsurvival.net
Good reading.
Bob Davis
WHAT'S NEW: A BAKER'S DOZEN ON HEPATITIS B
| Monday, 22nd of April 2013 |
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On the technical side, this series includes an interesting item from Outer Mongolia, where cold winter temperatures may affect the efficacy of the hep B vaccine, which cannot be frozen. From China and Viet Nam, there is interesting work on hep B, which is highy heat stable, used outside the cold chain.
The chronic carrier state of hep B makes it an unattractive candidate for early eradication, but eradication may become more attractive in future decades, as fresh birth cohorts are protected in greater numbers, and remaining hep B carriers in older age groups play a declining role in transmission of the virus.
A recent Cochrane review shows no RCTs evaluating hep B boosters. For all recently introduced vaccines, the same question arises: how durable is durable protection?
Read it all at www.childsurvival.net
Good reading.
Bob Davis
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| www.measlesinitiative.org www.technet21.org www.polioeradication.org www.globalhealthlearning.org www.who.int/bulletin allianceformalariaprevention.com www.malariaworld.org http://www.panafrican-med-journal.com/ |