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NEW THIS THURSDAY: A CRITICAL LITERATURE REVIEW OF HEALTH ECONOMIC EVALUATIONS OF ROTAVIRUS VACCINATIONS

Wednesday, 26th of June 2013 Print
  • A CRITICAL LITERATURE REVIEW OF HEALTH ECONOMIC EVALUATIONS OF ROTAVIRUS VACCINATIONS

S. Aballea et al., Human Vaccines & Immunotherapeutics, Vol. 9:6, June 2013

Abstract below; full text is available to journal subscribers.

Two licensed vaccines are available to prevent RVGE in infants. A worldwide critical review of economic evaluations of these vaccines was conducted. The objective was to describe differences in methodologies, assumptions and inputs and determine the key factors driving differences in conclusions. 68 economic evaluations were reviewed. RV vaccination was found to be cost-effective in developing countries, while conclusions varied between studies in developed countries. Many studies found that vaccination was likely to be cost-effective under some scenarios, such as lower prices scenarios, inclusion of herd protection, and/or adoption of a societal perspective. Other reasons for variability included uncertainty around healthcare visits incidence and lack of consensus on quality of life (QoL) valuation for infants and caregivers. New evidence on the vaccination effectiveness in real world, new ways of modelling herd protection and assessments of QoL in children could help more precisely define the conditions under which RV vaccination would be cost-effective in developed countries.



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