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NEW THIS THURSDAY: EFFECTS OF CIRCUMCISION ON MALE SEXUAL FUNCTIONS: SYSTEMATIC REVIEW

Tuesday, 27th of August 2013

• EFFECTS OF CIRCUMCISION ON MALE SEXUAL FUNCTIONS: A SYSTEMATIC REVIEW AND META-ANALYSIS

Asian J Androl. 2013 Jun 10. doi: 10.1038/aja.2013.47. [Epub ahead of print]

Tian Y, Liu W, Wang JZ, Wazir R, Yue X, Wang KJ.

Source

Department of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.

Abstract below; full text available to journal subscribers

This meta-analysis was performed to assess sexual functions following adult male circumcision. We searched the Cochrane Central Register of Controlled Trials, PUBMED, EMBASE, the Cochrane Database of Systematic Review and Web of Science from their inception until January 2013 to identify all eligible studies that reported on mens sexual function after circumcision. The Cochrane Collaborations RevMan 5.2 software was employed for data analysis, and the fixed or the random effect model was selected depending on the proportion of heterogeneity. We identified 10 studies, which described a total of 9317 circumcised and 9423 uncircumcised men who were evaluated for the association of circumcision with male sexual function. There were no significant differences in sexual desire (odds ratio (OR): 0.99; 95% confidence interval (CI): 0.92-1.06), dyspareunia (OR: 1.12; 95% CI: 0.52-2.44), premature ejaculation (OR: 1.13; 95% CI: 0.83-1.54), ejaculation latency time (OR: 1.33; 95% CI: 0.69-1.97), erectile dysfunctions (OR: 0.90; 95% CI: 0.65-1.25) and orgasm difficulties (OR: 0.97; 95% CI: 0.83-1.13). These findings suggest that circumcision is unlikely to adversely affect male sexual functions. However, these results should be evaluated in light of the low quality of the existing evidence and the significant heterogeneity across the various studies. Well-designed and prospective studies are required for a further understanding of this topic.Asian Journal of Andrology advance online publication, 10 June 2013; doi:10.1038/aja.2013.47.