Tuesday, 11th of January 2011 |
CSU 22/2011: HIV DECLINE IN ZIMBABWE
To what extent can the successes of Zimbabwe be replicated in other high prevalence countries of southern Africa?
Full text is at http://ije.oxfordjournals.org/content/39/5/1311.long
Good reading.
BD
HIV decline in Zimbabwe due to reductions in risky sex? Evidence from a comprehensive epidemiological review
1. Simon Gregson1,2,*, Elizabeth Gonese3,Timothy B Hallett1,Noah Taruberekera4, John W Hargrove5, Ben Lopman1, Elizabeth L Corbett6, Rob Dorrington7, Sabada Dube1, Karl Dehne8 and Owen Mugurungi3
+ Author Affiliations
1. 1Department of Infectious Disease Epidemiology, Imperial College London, London, UK, 2Biomedical Research and Training Institute, Harare, Zimbabwe, 3AIDS and TB Unit, Zimbabwe Ministry of Health and Child Welfare, Harare, Zimbabwe, 4Population Services International, Harare, Zimbabwe, 5ZVITAMBO Project, Harare, Zimbabwe, 6Clinical Research Unit, London School of Hygiene and Tropical Medicine, London, UK, 7Centre for Actuarial Research, University of Cape Town, Cape Town, South Africa and 8UNAIDS, Geneva1. *Corresponding author. Department of Infectious Disease Epidemiology, Imperial College London, Norfolk Place, London W2 1PG, UK. E-mail: sajgregson@aol.com
Abstract
Background Recent data from antenatal clinic (ANC) surveillance and general population surveys suggest substantial declines in human immunodeficiency virus (HIV) prevalence in Zimbabwe. We assessed the contributions of rising mortality, falling HIV incidence and sexual behaviour change to the decline in HIV prevalence.
Methods Comprehensive review and secondary analysis of national and local sources on trends in HIV prevalence, HIV incidence, mortality and sexual behaviour covering the period 1985–2007.
Results HIV prevalence fell in Zimbabwe over the past decade (national estimates: from 29.3% in 1997 to 15.6% in 2007). National census and survey estimates, vital registration data from Harare and Bulawayo, and prospective local population survey data from eastern Zimbabwe showed substantial rises in mortality during the 1990s levelling off after 2000. Direct estimates of HIV incidence in male factory workers and women attending pre- and post-natal clinics, trends in HIV prevalence in 15–24-year-olds, and back-calculation estimates based on the vital registration data from Harare indicated that HIV incidence may have peaked in the early 1990s and fallen during the 1990s. Household survey data showed reductions in numbers reporting casual partners from the late 1990s and high condom use in non-regular partnerships between 1998 and 2007.
Conclusions These findings provide the first convincing evidence of an HIV decline accelerated by changes in sexual behaviour in a southern African country. However, in 2007, one in every seven adults in Zimbabwe was still infected with a life-threatening virus and mortality rates remained at crisis level.
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