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Intestinal Immune Responses to Type 2 Oral Polio Vaccine (OPV) Challenge in Infants Previously Immunized with Bivalent OPV and Either High-Dose or Standard Inactivated Polio Vaccine

Friday, 24th of August 2018 Print

Intestinal Immune Responses to Type 2 Oral Polio Vaccine (OPV) Challenge in Infants Previously Immunized with Bivalent OPV and Either High-Dose or Standard Inactivated Polio Vaccine

Brickley EB1Strauch CB2Wieland-Alter WF3Connor RI4Lin S5Weiner JA5Ackerman ME5Arita M6Oberste MS7Weldon WC7Sáez-Llorens X8Bandyopadhyay AS9Wright PF3.

 

J Infect Dis. 2018 Jan 17;217(3):371-380. doi: 10.1093/infdis/jix556.

CONCLUSIONS:

Enhancing IPV-induced serum neutralization does not substantively improve intestinal mucosal immune responses or limit viral shedding on mOPV2 challenge.

 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853416/

 

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