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‘Since the introduction of the catch-up campaign there has been a marked attenuation in the frequency of cases.’
‘The lines show annual cumulative frequency curves for Invasive Pneumococcal Disease of serotypes 1, 4, 5, 6B, 7F, 9V, 14, 18C, 19F, 23F by week of year among children aged <5 years admitted to Kilifi District Hospital (KDH) who were residents of the Kilifi Health and Demographic Surveillance System. Routine immunization of children <12 months began on January 11, 2011 and the first round of catch-up vaccination took place between Jan 31-Feb 6, 2011. The year of vaccine introduction, 2011, is shown in a thicker line. Since the introduction of the catch-up campaign there has been a marked attenuation in the frequency of cases. However, the 8 baseline years show considerable variation in the number of cases year-on-year and it will take several years to be confident that changes in disease frequency are attributable to vaccine.’
Graphics at http://www.kemri-wellcome.org/pcvis-current%20disease%20surveillance