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Monday, 11th of March 2013 Print

Disease Eradication in the 21st Century: Implications for Global Health

Edited by Stephen L. Cochi and Walter R. Dowdle

September 2011 • 331 pp. • $38.00 • 978-0-262-01673-5

Disease eradication represents the ultimate in global equity and the defi nitive outcome of good public health practice. Thirty years ago, the elimination of smallpox defi ned disease eradication as a monumental global achievement with lasting benefi ts for society. Today, the global commitment to eradicate polio and guinea worm and heightened interest in the potential eradication of other infectious diseases, including measles/rubella, lymphatic fi lariasis, onchocerciasis, and malaria, dominate public health concerns. But what does it take to eradicate a disease? This book takes a fresh look at the evolving concepts of disease eradication, influenced by scientifi c advances, field experience, societal issues, and economic realities. A diverse group of experts from around the world,representing a range of disciplines, examines the biological, social, political, and economic complexities of eradicating a disease.

The book details lessons learned from the initiatives against polio, measles/rubella, and onchocerciasis. Further chapters examine ethical issues, the investment case, governance models, organizational and institutional arrangements, political and social factors, feasibility of eradication goals, priority setting, and the integration of disease eradication programs with existing health systems.


1 The Eradication of Infectious Diseases: Understanding the Lessons and Advancing Experience

Stephen L. Cochi and Walter R. Dowdle

Lessons Learned from Current Elimination and Eradication Initiatives


2 Lessons from the Late Stages of the Global Polio Eradication Initiative

R. Bruce Aylward

3 Measles and Rubella Eradication in the Americas: Seasoned Strategies for Sustained Success

Jon Kim Andrus, Ciro A. de Quadros, Carlos Castillo-Solórzano, Mirta Roses Periago,

and Donald A. Henderson


4 Onchocerciasis: From Control to Possible Eradication

Adrian Hopkins

Critical Issues in Determining Feasibility of Eradication

5 Political and Social Determinants of Disease Eradication

Robert G. Hall

6 The Role of Research

Julie Jacobson

7 Group Report: Assessing the Feasibility of an Eradication Initiative

Peter Strebel, Eric A. Ottesen, Ciro A. de Quadros, Sherine Guirguis, Robert G. Hall, Linda Muller,

Jai Prakash Narain, and Ole Wichmann

Issues in the Development of an Eradication Investment Case

8 The Moral Case for Eradication

Claudia I. Emerson

9 Economic Evaluation of the Benefits and Costs of Disease Elimination and Eradication Initiatives

Kimberly M. Thompson and Radboud J. Duintjer Tebbens

10 Group Report: Developing an Eradication Investment Case

Kimberly M. Thompson, Regina Rabinovich, Lesong Conteh, Claudia I. Emerson, B. Fenton Hall,

Peter A. Singer, Maya Vijayaraghavan, and Damian G. Walker

11 Guidelines for Preparing an Eradication Investment Case

Damian G. Walker and Regina Rabinovich


12 Governance Models for Eradication Initiatives

Kari Stoever

13 Managing Neglected Tropical Disease Partnerships

Andy Wright

14 Group Report: Elements of Good Governance in Disease Eradication Initiatives

Kari Stoever, Chris Maher, R. Bruce Aylward, Julie Jacobson, Ali Jaff er Mohamed, T. Jacob John,

Robert S. Scott, and Andy Wright

Disease Eradication and Health Systems

15 Integration of Eradication Initiatives and Health Systems

Alan R. Hinman

16 How Can Elimination and Eradication Initiatives Best Contribute to Health

Systems Strengthening?

Stewart Tyson and Robin Biellik

17 The Impacts of Measles Elimination

Activities on Immunization Services and Health Systems in Six Countries

Piya Hanvoravongchai, Sandra Mounier-Jack, Valeria Oliveira Cruz, Dina Balabanova, Robin Biellik,

Yayehyirad Kitaw, Tracey Koehlmoos, Sebastião Loureiro, Mitike Molla, Ha Trong Nguyen, Pierre

Ongolo-Zogo, Umeda Sadykova, Harbandhu Sarma, Maria Gloria Teixeira, Jasim Uddin, Alya Dabbagh, and 

Ulla Kou Griffiths

18 Disease Eradication as a Springboard for Broader Public Health Communication

Jeffrey Bates, Sherine Guirguis, Thomas Moran,and Lieven Desomer

19 Group Report: Designing Elimination or Eradication Initiatives that Interface

Eff ectively with Health Systems

Muhammad Ali Pate, John O. Gyapong,Walter R. Dowdle, Adrian Hopkins, Dairiku Hozumi,

Mwelecele Malecela, and Stewart Tyson